产品货号：
GS4819
中文名称：
重组人IL-2
英文名称：
Recombinant Human Interleukin-2
产品规格：
10μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 15.4kDa,a single non-glycosylated polypeptide chain containing 133 amino acids.
储存条件：冷冻（-20℃）
概述
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation.It is expressed by CD4+ and CD8+ T cells,γδ T cells,B cells,dendritic cells,and eosinophils.IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response.The receptor for IL-2 consists of three subunits(55 kDa IL-2Rα,75 kDa IL-2Rβ,and 64 kDa common gamma chain γc/IL-2Rγ)that are present on the cell surface in varying preformed complexes.Mature human IL-2 shares 56%and 66%amino acid sequence identity with mouse and rat IL-2,respectively.Human and mouse IL-2 exhibit cross-species activity.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人IL-2，IL-2, Human，Recombinant Human Interleukin-2
储存条件：冷冻（-20℃）
概述
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation.It is expressed by CD4+ and CD8+ T cells,γδ T cells,B cells,dendritic cells,and eosinophils.IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response.The receptor for IL-2 consists of three subunits(55 kDa IL-2Rα,75 kDa IL-2Rβ,and 64 kDa common gamma chain γc/IL-2Rγ)that are present on the cell surface in varying preformed complexes.Mature human IL-2 shares 56%and 66%amino acid sequence identity with mouse and rat IL-2,respectively.Human and mouse IL-2 exhibit cross-species activity.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.1ng/ml,corresponding to a specific activity of>1.0×107 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 5.0. |
| 内毒素 | Less than 1.0 EU/μg of rHuIL-2 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled H2O to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.Do not reconstitute in cell culture media directly. |
| 氨基酸序列 | APTSSSTKKT QLQLEHLLLD LQMILNGINN YKNPKLTRML TFKFYMPKKA TELKHLQCLE EELKPLEEVL NLAQSKNFHL RPRDLISNIN VIVLELKGSE TTFMCEYADE TATIVEFLNR WITFCQSIIS TLT |
相关搜索：重组人IL-2，IL-2, Human，Recombinant Human Interleukin-2